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Year : 2013  |  Volume : 27  |  Issue : 1  |  Page : 3-8

Involvement of microRNA in Asthma: New perspective in respiratory biology


Molecular Immunogenetics Laboratory and Centre of Excellence for Translational Research in Asthma and Lung Disease, Council of Scientific and Industrial Research (CSIR)-Institute of Genomics and Integrative Biology, Delhi

Correspondence Address:
Balaram Ghosh
Molecular Immunogenetics Laboratory and Centre of Excellence for Translational Research in Asthma and Lung Disease, Council of Scientific and Industrial Research (CSIR)-Institute of Genomics and Integrative Biology, Mall Road, Delhi - 110 007

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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0972-6691.116603

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A new insights have come from studies in Caenorhabditis elegans, in which researchers have identified a new endogenous class of small noncoding RNA (22-25 nucleotides), termed as microRNAs (miRNAs) as developmental regulators. Here, we discuss some recent studies demonstrating the role of miRNAs in asthma, with the anticipation that these studies were likely to influence treatment, diagnosis, and management of asthma and other inflammatory disorders. use of miRNAs as a therapy, the use of miRNAs holds great promise as a new treatment. Future of miRNA-based therapy in case of pulmonary disorders, such as asthma, chronic obstructive pulmonary disease (COPD), acute lung injury (ALI), and acute respiratory distress syndrome (ARDS) seems to be promising as indicated by animal studies.


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