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Year : 2012  |  Volume : 26  |  Issue : 1  |  Page : 14-15

Miracle of magnesium sulfate

Department of Emergency Medicine, PESIMSR, Kuppam, Chittoor District, Andhra Pradesh, India

Correspondence Address:
P Mohammed Shabbir
Department of Emergency Medicine, PESIMSR, Kuppam, Chittoor District, Andhra Pradesh - 517 425
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0972-6691.104440

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A 55 year old female patient, known asthmatic from past ten years, presented to us with history of breathlessness from past five days, cough with expectoration from past five days. On examination patient had severe bronchospasm, tachypnea, respiratory distress, silent chest and her SpO 2 75% on room air. Patient given conventional anti-asthmatics and antibiotics bronchospasm did not relive and SpO 2 did not improve therefore patient intubated paralyzed and put on control mode of ventilation with 100% O 2 patient SpO 2 was between 80 to 85% with persistent bronchospam. Patient continued to have bronchospasm for next 18 hrs even after continued antiasthmatics with steroids. After 18 hrs patient was started on i.v. Magnesium sulfate, 40 mg/kg bolus over 30mins. And 20 mg/kg infusion over 4hrs.patient responded within one hour of treatment bronchospasm decreased patient SpO 2 improved to 95%. Magnesium sulfate infusion continued for next 24 hrs patient was symptoms free, patient extubated observed for next 12 hrs and shifted out of ICU with normal clinical parameters. Hence it may be concluded that i.v. Magnesium sulfate can be considered for patient with acute severe asthma who do not respond to regular anti-asthmatics.

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