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Year : 2015  |  Volume : 29  |  Issue : 1  |  Page : 24-27

Sensitization to plant food allergens in patients with asthma

1 Department of Immunology, Allergy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
2 Devision of Allergy, Allergy Clinic of Shooshtari, Shiraz University of Medical Sciences, Shiraz, Iran

Correspondence Address:
Shirin Farjadian
Department of Immunology, Allergy Research Center, Shiraz University of Medical Sciences, Shiraz
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0972-6691.162975

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Purpose: Hypersensitivity to fruits and vegetables is assumed to play a role in the etiology and deteriorating of asthma symptoms in some patients, little is known about allergy to some fruits and vegetables in patients with asthma. The purpose of this study was to identify probable sensitization to eggplant, Shiraz grape, melon, and mango in patients with asthma. Materials and Methods: The study included 50 patients with moderate to severe persistent asthma and 50 healthy individuals with no history of asthma and atopic diseases. Skin tests were performed in both patient and control group with fresh eggplant, Shiraz grape, melon, and mango as well as the commercial extracts of mango and melon. Results: Among patients with asthma, the most frequent positive skin tests were to eggplant (48%), fresh melon (30%) and extracts of melon and mango (18% for each) which all were significantly different from the control group. Skin sensitization to Shiraz grape and fresh mango showed no difference to control group. Skin tests of 21 patients (42%) were negative to the all tested allergens. Conclusion: Forty percent of our patients had clinical symptoms to eggplant and more than half of those revealed positive skin tests to a fresh extract of this plant.

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