| CASE REPORT |
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| Year : 2018 | Volume
: 32
| Issue : 1 | Page : 34-38 |
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Fatal peripheral T-cell lymphoma presenting as hypereosinophilia and spontaneous tumor lysis syndrome: A rare case report
Majed B Momin1, Abhijeet Ingle1, G Vamshi Krishna Reddy2, Anamika Aluri2, B Saroj Kumar Prusty3
1 Department of Pathology, Yashoda Hospitals, Malakpet, Hyderabad, Telangana, India
2 Department of Medical Oncology, Yashoda Hospitals, Malakpet, Hyderabad, Telangana, India
3 Department of Critical Care Medicine, Yashoda Hospitals, Malakpet, Hyderabad, Telangana, India
Correspondence Address:
Dr. Majed B Momin
C/O. Abbas Apartment, 16-2-668/1/A, New Malakpet, Nalgonda X-Roads, Hyderabad - 500 036, Telangana
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/ijaai.ijaai_1_17
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Peripheral T-cell lymphomas (TCLs) are a heterogeneous group of aggressive, uncommon forms of T-cell or natural killer cell-derived non-Hodgkin's lymphomas. Acute tumor lysis syndrome (TLS) is a multiple metabolic derangement that occurs due to the treatment of malignancies or spontaneous tumor cell death. We report the case of a 56-year-old male patient who presented with marked eosinophilic leukocytosis, rash, and lymphadenopathy at the initial visit but finally manifested with TCL and spontaneous TLS. On the first visit, hemogram showed a marked eosinophilic leukocytosis and raised lactate dehydrogenase. The patient refused for admission; however, lymph node biopsy was done on day-care basis. After 3 days, the patient presented in the emergency room with shortness of breath, altered renal and liver parameters, and dyselectrolytemia. Based on histopathological with immunohistochemistry findings on lymph node biopsy and clinical and laboratory finding, the patient was diagnosed as TCL-not otherwise specified with TLS.
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